Catalytic Transfer Hydrogenation and its Applications in Organic Synthesis

Shu Chang, Zheng Chunzhi, Wang Rijie^*, Zhang Jiyan
(School of Chemical Engineering & Technology, Tianjin University Tianjin 300072)

Abstract Catalytic transfer hydrogenation (CTH) is an effective reduction method, which conducts at a mild reaction condition and with simple facilities comparing to common catalytic hydrogenation. In this article, the mechanism of CTH and the main reaction factors including catalyst, hydrogen donor, temperature and solvent were reviewed, the applications of CTH in organic synthesis were summarized, and the future prospect of CTH was analyzed.
Key word Catalytic transfer hydrogenation, Mechanism, Hydrogen donor, Application

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