Synthesis and Biological Activities of Pyrimethanil Salts

Wang Huifang¹,  Sun Xiaohong^1,2*,
(¹Chemical Research Institute,  ²Chemistry and Engineering Institute, Northwest University,  Xi’an  710069)
Liu Yuanfa³,  Chen Bang³,  Yang Jianwu¹
(³Department of Chemistry, Northwest University,  Xi’an  710069)

Abstract  Twelve pyrimethanil organic salts have been synthesized. Eleven of them are reported for the first time. Their preliminary toxicities have been tested by asp-agar-diluted method. The results showed that they exhibited excellent fungicidal activities. The relationship between the structures and the activities of these compounds has been discussed.
Key words  Synthesis,  Pyrimethanil salts,   Toxicity test,  Fungicidal activities

嘧霉胺盐的合成及其生物活性研究

王慧芳1   孙晓红^1,2*  刘源发³  陈 邦³  杨建武¹
(¹西北大学化学研究所  ²西北大学化工学院  ³西北大学化学系  西安  710069)

摘要  报道了12个具有生物活性的有机酸嘧霉胺盐，其中11个为首次合成的新化合物。采用琼脂稀释法测试了它们的生物活性，结果表明这些嘧霉胺盐对棉花、黄瓜、西瓜以及番茄枯萎病菌均具有较好的抑制作用。初步探讨了化合物结构中酸的结构与生物活性的相互关系。
关键词   合成  嘧霉胺盐  毒力测试  杀菌性能

王慧芳  女，26岁，硕士生，现从事有机合成研究。*联系人   E-mail: xhsun888@yahoo.com.cn
陕西省自然科学基金资助项目(2001H11)
2003-06-11收稿，2003-09-28接受

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