Synthesis and Characterization of Thermo- and pH-Sensitive b-Cyclodextrin Containing Polymer Huang Yi, Fan Xiaodong, Hu Hui (Department of Chemical Engineering, Northwestern Polytechnical University, Xi’an 710072) Abstract A novel b-cyclodextrin (b-CD) containing linear polymer (PDMA-b-CD) which has both thermo- and pH-sensitives was synthesized by quaternization of N,N-dimethylaminoethyl methacrylate(DMA) using iodide substituted b-CD as quaternizing agent. The polymer was characterized by FT-IR, 1H NMR and element analysis. The aqueous solubility experiments show that the polymer with 30.43(wt)% b-CD still exhibits pH-, ionic strength-and thermo-sensitivities. However, due to the introduction of hydroxyl groups in b-CD, and quaternizing tertiary amine groups, the aqueous solubility behavior of novel polymer synthesized, in response to the external stimuli, was much weaker than that of PDMA. The inclusion property of PDMA-b-CD was confirmed by the method of UV-vis spectrophotometric titration using phenolphthalein as probe. Key words b-Cyclodextrin, N,N-Dimethylaminoethyl methacrylate, Thermo- and pH-sensitive properties, Inclusion 线性b -环糊精高聚物的合成及性能研究 黄怡 范晓东 胡晖 (西北工业大学化工系 西安 710072) 摘要 采用季铵化反应将 6-碘代b-环糊精(b-CD-6-I)固载到聚甲基丙烯酸-N,N-二甲氨基乙酯(PDMA)线性高分子链上，合成出新型的b-环糊精线性高聚物。用核磁共振,红外光谱及元素分析对该聚合物的结构和组成进行了表征。聚合物的水溶性研究结果表明，环糊精含量为 30.43(wt)%时该聚合物仍具有较好的 pH、温度及离子强度敏感性。与酚酞的包合实验表明，该聚合物同时还具有一定的包合配位作用。 关键词 b-环糊精 聚甲基丙烯酸-N,N-二甲氨基乙酯 环境响应性 包合作用 黄怡 女，40 岁，副教授，从事有机合成及功能高分子材料的研究。*联系人 E-mail: xgdhy@126.com 陕西省自然科学基金资助项目(2000H11) 2003-10-26 收稿，2004-03-02 接受 (PDF全文下载c04112)