Determination of Cefaclor by Differential Pulse Voltammetry Yan Jinlong, Xu Qi (Department of Chemical Engineering, Yancheng Institute of Technology, Yancheng 224003) Abstract In the medium of 0.50mol/L NaOH solution, a sensitive differential pulse voltammetric peak of cefaclor (CFC) at mercury film electrode at about –0.85V(vs Ag/AgCl) was found. The electrochemical behavior and reaction mechanism of this system have been studied by cyclic voltammetry and differential pulse voltammetry. There is a good linear relationship between the peak current and the concentration of CFC in the range of 1.0×10-8～5.0×10-6mol/L. The detection limit of the method is 5.0×10-9mol/L. The concentration of CFC in Xinkenuo has been determined with good results by this method. Key words Cefaclor, Differential pulse voltammetry, Determination 微分脉冲伏安法测定头孢克洛 严金龙 许 琦 (盐城工学院化学工程系 江苏盐城 224003) 摘要 研究了 0.50mol/L NaOH 溶液中，头孢克洛碱性降解产物在汞膜电极上的电化学行为，并依此建立了头孢克洛微分脉冲伏安测定法。头孢克洛碱性降解产物在汞膜电极上具有明显的吸附性，于～-0.85V(vs Ag/AgCl)处出现一灵敏的阴极还原峰。峰高与头孢克洛的浓度在 1.0×10-8～5.0×10-6mol/L 范围内有良好的线性关系。方法的检出限为 5.0×10-9mol/L，用于欣可诺中头孢克洛含量的测定，结果满意。 关键词 头孢克洛 微分脉冲伏安法 测定 严金龙 男，32 岁，讲师，从事分析化学的教学和科研工作。 (PDF全文下载c04029)