Synthesis and Biological Activities of Pyrimethanil Salts Wang Huifang1, Sun Xiaohong1,2*, (1Chemical Research Institute, 2Chemistry and Engineering Institute, Northwest University, Xi’an 710069) Liu Yuanfa3, Chen Bang3, Yang Jianwu1 (3Department of Chemistry, Northwest University, Xi’an 710069) Abstract Twelve pyrimethanil organic salts have been synthesized. Eleven of them are reported for the first time. Their preliminary toxicities have been tested by asp-agar-diluted method. The results showed that they exhibited excellent fungicidal activities. The relationship between the structures and the activities of these compounds has been discussed. Key words Synthesis, Pyrimethanil salts, Toxicity test, Fungicidal activities 嘧霉胺盐的合成及其生物活性研究 王慧芳 1 孙晓红 1,2* 刘源发 3 陈 邦 3 杨建武1 (1 西北大学化学研究所 2西北大学化工学院 3 西北大学化学系 西安 710069) 摘要 报道了 12 个具有生物活性的有机酸嘧霉胺盐，其中 11 个为首次合成的新化合物。采用琼脂稀释法测试了它们的生物活性，结果表明这些嘧霉胺盐对棉花、黄瓜、西瓜以及番茄枯萎病菌均具有较好的抑制作用。初步探讨了化合物结构中酸的结构与生物活性的相互关系。 关键词 合成 嘧霉胺盐 毒力测试 杀菌性能 王慧芳 女，26 岁，硕士生，现从事有机合成研究。*联系人 E-mail: xhsun888@yahoo.com.cn 陕西省自然科学基金资助项目(2001H11) 2003-06-11 收稿，2003-09-28 接受 (PDF全文下载c04033)