Synthesis of Ethyl Crotonate by Microwave Catalysis

Shao Shixiang, Zhang Tingting, Chen Huanxin, Fan Jinyan, Meng Qing
(Department of Biotechnology and Chemical Engineering, Tianjin Institute of Technology, Tianjin 30019)

Abstract Ethyl crotonate was synthesized by esterification of crotonic acid with alcohol in the presence of microwave system. The optimal conditions of the microwave catalysis were determined by means of orthogonal experimental design. Several experimental factors such as reaction time, alcohol-acid ratio, were discussed. The result showed that the reaction rate could be accelerated by microwave impulse.
Key words Microwave chemistry, Esterification, Ethyl crotonate

微波催化合成巴豆酸乙酯

摘要 在微波系统中，由巴豆酸和乙醇进行酯化反应制备巴豆酸乙酯，并且由正交实验法确定了微波催化的最佳反应条件。结果表明，微波可明显加速该酯化反应的速率。
关键词 微波化学 巴豆酸乙酯 酯化反应