Present Situation and Problems of the Study on Supercritical Anti-solvent Process

Li Zhiyi, Zhang Xiaodong, Hu Dapeng, Liu Xuewu
(Dalian University of Technology, Dalian 116012)

Abstract Supercritical Anti-Solvent (SAS) process has been proposed recently to prepare micro-and nano-particles by supercritical fluids. After a brief description of the present situation and the potential applications of the process, the paper gives a detailed analysis of the limitations of the published research works, and points out the necessity of the fundamental study and the main problems to be solved.
Key words Anti-solvent process, Supercritical fluid, Mass transfer

超临界反溶剂过程的若干问题