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The New Progress in the Studies on Antibacterial Properties of Schiff Bases and its Metal Complexes Wang Jianhua, Lei Wen#, Wang Yuanliang Abstract Schiff bases and its
transition metal complexes have significant antiviral and antibacterial activities. In
order to screen the high-activity antibiotic drugs with low toxicity, a large number of
Schiff bases and its metal complexes have been synthesized, and the bioactivity screening
of these ligands and complexes were done against different bacterial species. The research
progress of antimicrobial activities of some kinds of Schiff base and its metal complexes
are presented. The problems in the study on Schiff bases' antibacterial activities and the
way of solutions are summarized and the prospects of the research methods are described.
Schiff碱及其金属配合物的抑菌活性 王建华 雷 文# 王远亮 摘要 Schiff碱及其过渡金属配合物具有独特的抗病毒、抑制细菌生长等生物活性。为筛选高效低毒的抗菌剂，人们合成了大量不同类型的Schiff碱及其金属配合物，并对不同菌株的抑制作用进行了研究；本文介绍了近年来国内外Schiff碱及其金属配合物的抑菌活性研究，总结了Schiff碱抑菌活性研究中所存在的问题及解决的方法，并就其研究方法进行了展望。 王建华 男，39岁，副教授，从事生物无机化学的研究。E-mail:cquwjh@163.net |