| 祖木热提·穆合塔尔,刘洋,刘尊奇.化学通报,2026,89(2):129-141. |
| 纳米纤维素的制备及其在生物医学领域的应用研究进展 |
| Applications of Nanocellulose - Based Materials in the Biomedical Field: Drug Delivery, Wound Healing, and Tissue Engineering |
| 投稿时间：2025-07-22 修订日期：2025-11-18 |
| DOI： |
| 中文关键词: 纳米纤维素 药物递送 伤口愈合 组织工程 |
| 英文关键词:Nanocellulose Drug Delivery Wound Healing Tissue Engineering |
| 基金项目:新疆维吾尔自治区两区项目(2022LQ01008)、新疆维吾尔自治区重点研发专项(20220B0204-3,2022B02033-3)、新疆维吾尔自治区 自然科学基金面上项目(2022D01A76)、新疆农业化学与生物材料重点实验室开放课题基金项目(KF202206)、国家自然科学基金项目 (21561030)和新疆“天山英才”计划项目资助 |
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| 中文摘要: |
| 纳米纤维素作为一种来源广泛、生物相容性良好且可生物降解的天然高分子材料，在生物医学领域展现出广阔的应用前景。本文系统综述了纳米纤维素的制备方法及其结构特性，重点探讨了基于纳米纤维素的微粒、纤维、薄膜、水凝胶和气凝胶等材料的构建策略与功能化设计。在应用方面，纳米纤维素基材料凭借其高载药能力、可控释放性能和仿生结构特性，在药物递送、伤口愈合和组织工程领域得到广泛应用。文章同时分析了当前该材料面临的挑战，并展望了未来发展。本综述旨在推动纳米纤维素在生物医学领域的深入应用，为疾病治疗和组织修复提供切实有效的方案。 |
| 英文摘要: |
| Nanocellulose, a natural polymeric material with extensive sources,excellent biocompatibility, and biodegradability, exhibits significant application potential in the biomedical field. This article systematically reviews the preparation methods and structural characteristics of nanocellulose, with a focus on the construction strategies and functional design of nanocellulose-based materials such as microparticles, fibers, films, hydrogels, and aerogels. In practical applications, nanocellulose-based materials are widely utilized in drug delivery, wound healing, and tissue engineering owing to their high drug-loading capacity, controllable release, and biomimetic structural features. The article also discusses the current challenges faced by these materials and prospects for future development. This review aims to promote the broader application of nanocellulose in biomedicine and provide practical and effective solutions for disease treatment and tissue repair. |
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